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HOOFDZAKEN on a working visit in ERIBA05 Jul. 2022On April 12 people of the “HOOFDZAKEN” organisation were on a working visit in ERIBA. “Hoofdzaken”is a collaboration between de Hersenstichting, MIND, ZonMW,NWO and LSH/Health Holland. View the link for the article about the visit (in Dutch) https://www.hoofdzaken.nl/n -
cGAS-STING drives IL6-dependent survival of chromosomally instable cancers20 Jun. 2022cGAS-STING drives IL6-dependent survival of chromosomally instable cancers by Christy Hong, et al Chromosomal instability (CIN), the tendency of cells to misdistribute chromosomes during mitosis, is a hallmark feature of cancer cells. As healthy cells rarely display CIN, targeting cells with CIN i -
The developmental stage of the medulloblastoma cell-of-origin restricts Hedgehog pathway usage and drug sensitivity10 Jun. 2022The developmental stage of the medulloblastoma cell-of-origin restricts Hedgehog pathway usage and drug sensitivity A study by Smit, Martini et al. Out now in Journal of Cell Science – SHH medulloblastoma, a type of brain cancer, originates from the cerebellar granule neuron progenit -
UMCG’s ERIBA joins forces with the UK MSD Discovery Centre for boosting resilience to age-related neurodegeneration10 May. 2022UMCG’s ERIBA joins forces with the UK MSD Discovery Centre for boosting resilience to age-related neurodegeneration Researchers from the UMCG European Institute of Biological Ageing (ERIBA) recently started a collaboration with the MSD Discovery Centre in London. Together they will investigate the -
Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding26 Apr. 2022Christine Müller, Laura M. Zidek, Sabrina Eichwald, Gertrud Kortman, Mirjam H. Koster and Cornelis F. Calkhoven eLife 2022; 11: e62625 DOI: 10.7554/eLife.62625 Obesity is usually characterized by fat accumulation in enlarged – hypertrophic – adipocytes that are a source of inflammatory medi -
Marie Skłodowska-Curie Doctoral Network grant to Eugene Berezikov12 Apr. 2022REGENERATE-IT: learning from animals how to regenerate Eugene Berezikov received a Marie Skłodowska-Curie Doctoral Network (DN) grant and will coordinate the project entitled REGENERATE-IT, which brings together researchers working on different regenerative model organisms in order to understand -
C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cells18 Jan. 2022Britt A. Sterken, Tobias Ackermann, Christine Müller, Hidde R. Zuidhof, Gertrud Kortman, Alejandra Hernandez-Segura, Mathilde Broekhuis, Diana Spierings, Victor Guryev & Cornelis F. Calkhoven. C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cell -
KWF grant for Marco Demaria22 Dec. 2021The project done in the Demaria lab will explore sex-dependent differences in the accumulation of senescent cells in the liver and the relevance for development and progression of aggressive liver cancers. See link for more information: Ruim €1,7 miljoen van KWF voor 3 UMCG-onderzoeken &nbs -
Cor Calkhoven has received a grant from the Dutch Cancer Society (KWF)22 Dec. 2021Cor Calkhoven has received a grant from the Dutch Cancer Society (KWF). The proposed research aims to investigate the oncogenic mechanisms behind the upregulation of the transcription factor C/EBPβ-LIP in Triple-Negative Breast Cancer (TNBC) and its function in cancer immune evasion. See the link f
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Inspiration video sustainability challenge-Jennefer Beenen14 Dec. 2021Hanze University of Applied Sciences has integrated the “Sustainable Development Goals” into their education, research and operational management. End of October this year, the Institute for Life Science & Technology (ILST) started the ILST Sustainability Challenge during which students, tea
