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A study by Bočkaj, Martini, and de Camargo Magalhães et al. Out now in PLoS Genetics – The discovery that mutations in histone H3 variants frequently occur in malignant pediatric glioma created great interest into the mechanism of transformation of these so-called oncohistones. Yet whereas m

How aging causes relatively common diseases such as Alzheimer’s and Parkinson’s is still a mystery. Since toxic structural changes in proteins are likely to be responsible, Pras et al. investigated biological mechanisms that could drive such changes. The authors made use of a modifying factor ca

In the Knowlands project by the RUG Pre-University Academy (Scholierenakademie), short movie clips and lesson packages were developed to reach year 3 and 4 of pre-university high schools (VWO) and teach about research skills. In the project, University of Groningen scientists from the alpha, beta an

Out now in Genes and Development (http://genesdev.cshlp.org/content/early/recent), a collaborative study from the Foijer lab at ERIBA and the Don Cleveland lab at the Ludwig Cancer Research Institute in San Diego, USA. This study describes how transient CIN induced by reversible Plk4 overexpression

Marco Demaria has received a Vidi grant of 800,000 euros from the Netherlands Organization for Scientific Research (NWO). This will enable him to develop a new line of research in the next five years within his research into the mechanisms of cell aging and its relationship with age-related diseases

Latest news from the group of VictorGuryev See for the whole article: https://umcgresearch.org/-/some-gene-ensembles-do-not-play-well-together-in-severe-covid-19-and-pneumonia-patients?inheritRedirect=true

The ERIBA Outreach Team consisting of Anton Steen, Eleni Fitsiou, Gerald de Haan, Josefine Hartung, Judith Paridaen, Karin van Wageningen, Katya Dvorianinova, Lale Güngördü, Megha Pandey-Upadhyay, Stijn Mouton and Sylvia Hoks, received the KNAW science communication grant for our public engagemen

Simon Renders from the German Cancer Research Center (DKFZ) together with PhD student Arthur Flohr Svendsen from the Ageing Biology and Stem Cells laboratory at ERIBA have describe the function of a gene firstly described in brain development – Neogenin-1 (Neo1) – in blood stem cells. In this re

In this study, Stijn Mouton and colleagues demonstrate that TIM29 is required for adapting to a highly proliferative state during regeneration in the flatworm Macrostomum lignano. In addition, they present how this model organism can be used to probe conserved genes with an unknown function for thei

A NWO-Open competition XS grant for groundbreaking projects was recently awarded to researcher Nynke Oosterhof in the group of Judith Paridaen. They will use this grant to develop a method to make a direct connection between in vivo imaging and single cell transcriptomics. If successful, this method